Epithelial-mesenchymal transition
نویسندگان
چکیده
Abstract The process of epithelial-mesenchymal transition (EMT) occurs in both physiological and pathological states, there are increasing links between EMT tumor progression. During this process, dynamic changes cell organization function occur that promote migration invasion. A better understanding the mechanism plastic may help develop novel targeted therapies can treat cancers varying degrees malignancy. Our review helps to systematize knowledge molecular biochemical mechanisms involved backgrounds.
منابع مشابه
Epithelial to mesenchymal transition concept in Cancer: Review article
Owing to this fact that most of the mortalities in cancers are as a result of metastasis, study on the involved pathways in metastasis including Epithelial to mesenchymal transition (EMT) would be so critical and important. Up to date, several extensive studies have been carried out to determine the correlation between EMT and cancer and their results have shown that the EMT plays pivotal role ...
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Pathology and NYU Cancer Institute, NYU Langone Medical Center, New York, New York; OSI Pharmaceuticals, Farmingdale, New York; Division of Matrix Biology, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts; Cold Spring Harbor Laboratory, Cold Spring Harbor, New York; and Department of Surgery, University of Melbourne, St. Vincent’s Hospi...
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ژورنال
عنوان ژورنال: Current Issues in Pharmacy and Medical Sciences
سال: 2023
ISSN: ['2084-980X', '2300-6676']
DOI: https://doi.org/10.2478/cipms-2023-0005